Engineered Disc-Like Angle-Ply Structures for Intervertebral Disc Replacement
نویسندگان
چکیده
منابع مشابه
Total disc replacement using a tissue-engineered intervertebral disc in vivo: new animal model and initial results
STUDY TYPE Basic science Introduction: Chronic back pain due to degenerative disc disease (DDD) is among the most important medical conditions causing morbidity and significant health care costs. Surgical treatment options include disc replacement or fusion surgery, but are associated with significant short- and long-term risks.1 Biological tissue-engineering of human intervertebral discs (IV...
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The most common reason that adults in the United States see their physician is lower back or neck pain secondary to degenerative disc disease. To date, approaches to treat degenerative disc disease are confined to purely mechanical devices designed to either eliminate or enable flexibility of the diseased motion segment. Tissue engineered intervertebral discs (TE-IVDs) have been proposed as an ...
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Recapitulation of the form and function of complex tissue organization using appropriate biomaterials impacts success in tissue engineering endeavors. The annulus fibrosus (AF) represents a complex, multilamellar, hierarchical structure consisting of collagen, proteoglycans, and elastic fibers. To mimic the intricacy of AF anatomy, a silk protein-based multilayered, disc-like angle-ply construc...
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Cramps in the affected leg are quite common and persistent although sciatic pain may have disappeared completely. A small proportion of patients develop a true recurrent prolapse (prolapse from the same disc) months to years later. This varies in individual statistics, but is probably in the neighbourhood of 4 per cent. to 5 per cent. These recurrent attacks of sciatica, due to a further protru...
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Idiopathic calcification of the intervertebral disc is a rare condition in childhood, of unknown etiology. Calcifications are occasionally discovered on routine radiological examination, or on investigation of nonspecific symptoms such as neck pain, torticollis, fever, and radiculopathy. We report a case of a 7-year-old boy with intervertebral disc calcification. Clinical and radiological signs...
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ژورنال
عنوان ژورنال: Spine
سال: 2010
ISSN: 0362-2436
DOI: 10.1097/brs.0b013e3181d74414